The Latest Journal Articles in Endocrinology

1Safety and efficacy of once weekly dulaglutide vs sitagliptin after two years in metformin-treated patients with type 2 diabetes (AWARD-5): A randomised, phase 3 studyDiabetes, Obesity and Metabolism, April 24, 2015  Clinical Article
2Simplicity, safety, and acceptability of insulin pen use versus the conventional vial/syringe device in patients with type 1 and type 2 diabetes mellitus in LebanonPatient Preference and Adherence, April 24, 2015  Full Text  Clinical Article
3Analysis of continuous glucose monitoring in pregnant women with diabetes: distinct temporal patterns of glucose associated with large-for-gestational-age infantsDiabetes Care, April 24, 2015  Clinical Article
4A randomized clinical trial to evaluate the efficacy and safety of co-administration of sitagliptin with intensively titrated insulin glargineDiabetes Therapy, April 24, 2015  Full Text  Clinical Article
5Let’s Empower and Prepare (LEAP): Evaluation of a Structured Transition Program for Young Adults With Type 1 DiabetesDiabetes Care, April 24, 2015  Clinical Article
6Continuous subcutaneous insulin infusion in diabetes: patient populations, safety, efficacy, and pharmacoeconomicsDiabetes/Metabolism Research and Reviews, April 24, 2015  Review Article
7The brain-derived neurotrophic factor (BDNF) Val66Met polymorphism is associated with increased body mass index and insulin resistance measures in bipolar disorder and schizophreniaBipolar Disorders, April 24, 2015  Clinical Article
8Circulating Cell Free Mitochondrial DNA (ccf-mtDNA) is Increased in coronary heart disease patients with diabetes mellitusJournal of Diabetes Investigation, April 24, 2015  Clinical Article
9Complementary and alternative medicines for diabetes mellitus management in ASEAN countriesComplementary Therapies in Medicine, April 24, 2015  Clinical Article
10Is calprotectin a novel biomarker of neuroinflammation in diabetic periferal neuropathy?Diabetology & Metabolic Syndrome, April 24, 2015  Full Text  Clinical Article
1Brainy Bones: New research reveals how our skeleton is a lot like our brainMonash University News, April 24, 2015
2New research shows how to tackle obesityThe University of Sheffield News, April 24, 2015
3Labels on the front of food packaging can enable healthier choices, new research findsUniversity of Surrey News, April 24, 2015
4Nanotech-enabled moisturizer speeds healing of diabetic skin woundsNorthwestern University News, April 24, 2015
5Researchers get under the skin to develop new transplant techniqueUniversity of Alberta Faculty of Medicine & Dentistry News, April 24, 2015
6Papers identify effective and cost-effective treatments for complex woundsSt. Michael's Hospital, April 24, 2015
7Fat signals control energy levels in the brainWashington University School of Medicine in St. Louis News, April 24, 2015
8VU team explores new cholesterol processing pathwayVanderbilt University Medical Center Research News, April 24, 2015
9Maternal gestational diabetes linked to autism risk for offspringKeck Medicine of USC News, April 24, 2015
10Race is variable in obesity's risk for prostate cancerUW Medicine, April 23, 2015

Show Me:

TNFR1 predicts all-cause mortality in diabetic kidney disease

As reported in Diabetes Care, type 2 diabetics (n=522) with diabetic kidney disease (eGFR< 60 or urinary albumin-to-creatinine ratio > 30 mg/mmol) with TNFR1 levels in the highest quartile were at increased risk of all-cause mortality compared to diabetics with TNFR1 levels in the lowest quartile (aHR = 2.98). One hundred ninety-six deaths occurred in 48 months of follow-up.

Vildegliptin superior to glimepiride when added to metformin

As reported in Metabolism, addition of vildegliptin (50 mg bid) to metformin in T2DM patients inadequately controlled on metformin alone was superior to the addition of glimepiride (2 mg tid) to metformin. Patients on the vildegliptin + metformin regimen lost more weight, had an improved lipid profile, had increased insulin sensitivity, and decreased post-prandial lipemia and insulinemia compared to patients on the glimepiride + metformin regimen.

Decreased survival in diabetic patients with pancreatic cancer

As reported in the British Journal of Cancer, patients with diabetes (n=62) are at increased risk of death from pancreatic cancer overall (HR=1.52) and within 3 years of diagnosis (HR=1.45).

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