Endocrinology News Articles

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Our Endocrinology medical editors have ranked and organized the top peer-reviewed clinical journals by topic including diabetes types 1 and 2, thyroid and glandular diseases, obesity and dyslipidemia. In a matter of minutes, you and all the members of your patient care team can stay current on the latest endocrine news literature as it is published.

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Ranked, sorted, and summarized by MDLinx editors from the latest literature

1 New insulin glargine 300 units/ml versus glargine 100 units/ml in people with type 2 diabetes using oral agents and basal insulin: Glucose control and hypoglycemia in a 6-month randomized controlled trial (EDITION 2) Diabetes Care, October 23, 2014    Clinical Article

2 Glucagon for hypoglycemic episodes in insulin-treated diabetic patients: a systematic review and meta-analysis with a comparison of glucagon with dextrose and of different glucagon formulations Acta Diabetologica, October 23, 2014    Evidence Based Medicine    Review Article

3 HbA1c as a predictor of diabetes and as an outcome in the diabetes prevention program: a randomized clinical trial Diabetes Care, October 23, 2014    Clinical Article

4 A pharmacogenetic association between a variation in calpain 10 (CAPN10) gene and the response to metformin treatment in patients with type 2 diabetes European Journal of Clinical Pharmacology, October 23, 2014    Clinical Article

5 Gastrointestinal metabolic surgery for the treatment of type 2 diabetes mellitus Full Text World Journal of Gastroenterology, October 23, 2014    Clinical Article

6 Changes in adipose tissue depots and metabolic markers following a one-year diet and exercise intervention in overweight and obese patients with type 2 diabetes Diabetes Care, October 23, 2014    Clinical Article

7 Metformin treatment to reduce central adiposity after prenatal growth restraint: a placebo-controlled pilot study in prepubertal children Pediatric Diabetes, October 23, 2014    Clinical Article

8 The benefits of insulin pump therapy in children and adolescents with type 1 diabetes Journal of Pediatric Nursing, October 23, 2014

9 Pharmacokinetics and clinical use of incretin-based therapies in patients with chronic kidney disease and type 2 diabetes Clinical Pharmacokinetics, October 23, 2014    Review Article

10 The spectrum of clinical presentation, diagnosis, and management of mitochondrial forms of diabetes Pediatric Diabetes, October 23, 2014    Review Article

11 Higher glucose concentrations following protein- and fat-rich meals - the Tuebingen Grill Study: a pilot study in adolescents with type 1 diabetes Pediatric Diabetes, October 23, 2014    Clinical Article

12 Therapeutic inertia: underdiagnosed and undertreated hypertension in children participating in the T1D Exchange Clinic Registry Pediatric Diabetes, October 23, 2014    Clinical Article

13 N1-methylnicotinamide as an endogenous probe for drug interactions by renal cation transporters: studies on the metformin–trimethoprim interaction European Journal of Clinical Pharmacology, October 23, 2014    Clinical Article

14 Association between braf v600e mutation and recurrence of papillary thyroid cancer Journal of Clinical Oncology, October 23, 2014    Clinical Article

15 Thyroid cancer mortality and incidence: A global overview International Journal of Cancer, October 23, 2014    Clinical Article

16 Statins, glycemia, and diabetes mellitus: Another point of view Current Atherosclerosis Reports, October 23, 2014    Clinical Article

17 Occupational characteristics and the progression of carotid artery intima-media thickness and plaque over 9 years: the Multi-Ethnic Study of Atherosclerosis (MESA) Occupational and Environmental Medicine, October 23, 2014    Clinical Article

18 The relationship between low maternal serum vitamin D levels and glycemic control in gestational diabetes assessed by HbA1c levels: An observational cross-sectional study Full Text BMC Pregnancy and Childbirth, October 23, 2014    Clinical Article

19 Brief training in patient-centered counseling for healthy weight management increases counseling self-efficacy and goal setting among pediatric primary care providers : results of a pilot program Clinical Pediatrics, October 23, 2014    Clinical Article

20 Bipolar disorder symptoms in patients seeking bariatric surgery Obesity Surgery, October 23, 2014    Clinical Article

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Highlights in Endocrinology

Parenteral vitamin D improves insulin sensitivity

As reported in Swiss Medical Weekly, supplemental vitamin D3 (300,000 IU im) in patients (n=55) with T2DM of > 10 y duration resulted in a 12.8% decrease in HOMA-IR at 6 months compared to an increase of 10% in patients who received placebo.

Vildegliptin superior to glimepiride when added to metformin

As reported in Metabolism, addition of vildegliptin (50 mg bid) to metformin in T2DM patients inadequately controlled on metformin alone was superior to the addition of glimepiride (2 mg tid) to metformin. Patients on the vildegliptin + metformin regimen lost more weight, had an improved lipid profile, had increased insulin sensitivity, and decreased post-prandial lipemia and insulinemia compared to patients on the glimepiride + metformin regimen.

TNFR1 predicts all-cause mortality in diabetic kidney disease

As reported in Diabetes Care, type 2 diabetics (n=522) with diabetic kidney disease (eGFR< 60 or urinary albumin-to-creatinine ratio > 30 mg/mmol) with TNFR1 levels in the highest quartile were at increased risk of all-cause mortality compared to diabetics with TNFR1 levels in the lowest quartile (aHR = 2.98). One hundred ninety-six deaths occurred in 48 months of follow-up.

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