1Diet quality and history of gestational diabetes mellitus among childbearing women, United States, 2007–2010Preventing Chronic Disease  Full Text  Review Article
2Anti-obesity pharmacotherapy and the potential for preventing progression from pre-diabetes to type 2 diabetesEndocrine Practice  Review Article
3Diabetes mellitus and its association with central obesity and disability among older adults: A global perspectiveExperimental Gerontology  Clinical Article
4Risk of microangiopathy in type 2 diabetes mellitus patients with or without chronic hepatitis C: Results of a retrospective long-term controlled cohort studyDigestive and Liver Diseases  Clinical Article
5Resting heart rate and the risk of type 2 diabetes: A systematic review and dose-response meta-analysis of cohort studiesNutrition, Metabolism & Cardiovascular Diseases  Evidence Based Medicine  Review Article
6Long-term exposure to air pollution and type 2 diabetes mellitus in a multiethnic cohortAmerican Journal of Epidemiology  Clinical Article
7Glucocorticoid receptor function in health and diseaseClinical Endocrinology  Review Article
8Impact of diabetes type II and chronic inflammation on pancreatic cancerBMC Cancer  Full Text  Clinical Article
9Sensor-based interactive balance training with visual joint movement feedback for improving postural stability in diabetics with peripheral neuropathy: a randomized controlled trialGerontology  Clinical Article
10Epigenetic regulation of PLAC8 contributes to altered function of endothelial colony forming cells exposed to intrauterine gestational diabetes mellitusDiabetes  Clinical Article
1FDA drug safety communication: FDA cautions about using testosterone products for low testosterone due to aging; requires labeling change to inform of possible increased risk of heart attack and stroke with useFDA What's New: Drugs
2Dramatic increases in diabetes incidence, costly care and redundant spending: Leading medical association responds to “unmanageable” situation, pushes Congress to pass improved diabetes care legislationCDC
3New fat cells created quickly, but losing them...Yale School of Medicine News
4Joslin scientists find direct link between insulin resistance in the brain and behavioral disordersJoslin Diabetes Center News
5SLU researcher prevents type I diabetes in labSaint Louis University Health News
6A new stem cell advanceHarvard Gazette - Health News
7WHO calls for worldwide use of "smart" syringesWHO news
8Interaction of estrogen receptor and coactivators seen for first timeBaylor College of Medicine News
9‘Feeding and fasting’ hormone adropin can improve insulin actionSaint Louis University Health News
10Neurons controlling appetite made from skin cellsColumbia University Medical Center

Show Me:

Decreased survival in diabetic patients with pancreatic cancer

As reported in the British Journal of Cancer, patients with diabetes (n=62) are at increased risk of death from pancreatic cancer overall (HR=1.52) and within 3 years of diagnosis (HR=1.45).

Aspirin has a dose-independent effect in T2DM

As reported in The International Journal of Clinical Practice, the dose of aspirin (75 mg/d, 300 mg/d, or 3.6 g/d) had an independent effect on markers of vascular inflammation, oxidative stress, insulin resistance, and endothelial function in patients with T2DM (n=17; mean age = 57.4 y).

TNFR1 predicts all-cause mortality in diabetic kidney disease

As reported in Diabetes Care, type 2 diabetics (n=522) with diabetic kidney disease (eGFR< 60 or urinary albumin-to-creatinine ratio > 30 mg/mmol) with TNFR1 levels in the highest quartile were at increased risk of all-cause mortality compared to diabetics with TNFR1 levels in the lowest quartile (aHR = 2.98). One hundred ninety-six deaths occurred in 48 months of follow-up.

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Clinical Pearls

Clinical Pearl from Smartest DocBile acids stimulate FGF19 and GLP-1 secretion and regulate hepatic insulin sensitivity to improve glucose tolerance.

Clinical Pearl from Smartest DocThiazolidinediones may promote fat mass gain.

Clinical Pearl from Smartest DocTissue compression is not characteristic of adiposopathy.

The Top Read Articles of 2014 are Now Available

Scouring thousands of peer-reviewed journals and popular press, Our Editors just released the Top Read Articles of the Year. See the Top Read List