Decreased survival in diabetic patients with pancreatic cancer
As reported in the British Journal of Cancer, patients with diabetes (n=62) are at increased risk of death from pancreatic cancer overall (HR=1.52) and within 3 years of diagnosis (HR=1.45).
Aspirin has a dose-independent effect in T2DM
As reported in The International Journal of Clinical Practice, the dose of aspirin (75 mg/d, 300 mg/d, or 3.6 g/d) had an independent effect on markers of vascular inflammation, oxidative stress, insulin resistance, and endothelial function in patients with T2DM (n=17; mean age = 57.4 y).
TNFR1 predicts all-cause mortality in diabetic kidney disease
As reported in Diabetes Care, type 2 diabetics (n=522) with diabetic kidney disease (eGFR< 60 or urinary albumin-to-creatinine ratio > 30 mg/mmol) with TNFR1 levels in the highest quartile were at increased risk of all-cause mortality compared to diabetics with TNFR1 levels in the lowest quartile (aHR = 2.98). One hundred ninety-six deaths occurred in 48 months of follow-up.