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See Latest ArticlesMigraine Chronification - Concept and Risk Factors
Discovery Medicine, 10/27/09
Bigal M – Migraine is a chronic disease with episodic attacks and a variable prognosis. In a subgroup, migraine evolves into a more protracted condition (migraine transformation or progression). Transformation of migraine may be subdivided into three partially overlapping forms. Clinical transformation describes the evolution from episodic into chronic migraine. Physiological transformation refers to alterations in nociceptive thresholds and in pain pathways that precede or accompany clinical transformation. Anatomical transformation refers to the emergence of definitive brain lesions (e.g., stroke and deep white matter lesions) in some migraineurs. Herein the author conceptualize migraine as a progressive disease and discuss risk factors for transformation.
Today in Basic Science...keeping you current
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Protection from sepsis-induced acute renal failure by adenoviral-mediated gene transfer of beta2-adrenoceptor
Nephrology Dialysis Transplantation, 11/05/09
Inhibition of NF-kB ameliorates sepsis-induced downregulation of aquaporin-2 / V2 receptor expression and acute renal failure in vivo
American Journal of Physiology: Renal Physiology, 10/15/09
Activated Protein C and Acute Kidney Injury: Selective Targeting of PAR-1
Current Drug Targets, 11/03/09
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Escitalopram and Venlafaxine for the Prophylaxis of Migraine Headache Without Mood Disorders
Clinical Neuropharmacology, 10/02/09
Stroke treatment with alteplase given 3·0—4·5 h after onset of acute ischaemic stroke (ECASS III): additional outcomes and subgroup analysis of a randomised controlled trial
The Lancet Neurology, 11/17/09
Safety and Efficacy of IV-TPA for Ischaemic Stroke in Clinical Practice - A Bayesian Analysis
Cerebrovascular Diseases, 10/30/09
Today in Pain Management...keeping you current
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Escitalopram and Venlafaxine for the Prophylaxis of Migraine Headache Without Mood Disorders
Clinical Neuropharmacology, 10/02/09
Use of intra-articular lidocaine as analgesia in anterior shoulder dislocation: a review and meta-analysis of the literature
Canadian Journal of Rural Medicine, 10/22/09
Diclofenac for acute pain in children
Cochrane Reviews, 10/08/09
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