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A new study by researchers has discovered abnormalities in the white matter of the brain that seem to be critical for the timing of schizophrenia. The white matter of the brain consists of nerve fibres that connect parts of the brain and help regulate behaviour. The normal brain develops in a back to front fashion, i.e. posterior regions mature first and the frontal lobes last. The research discovered that if there are very severe deficits in the white matter in these posterior regions, then schizophrenia develops early in adolescence. As people grow older their deficits "migrate" in a back to front manner and in adulthood, they impact the frontal lobes of the brain quite dramatically.


   

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