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New treatments for methicillin-resistant Staphylococcus aureus
Current Opinion in Critical Care, 09/14/09

Stryjewski ME et al. – Linezolid, daptomycin and tigecycline have been approved during the last decade to treat infections due to MRSA. Although these agents are extremely valuable in the fight against MRSA, each one has limitations. New lypoglycopeptides (telavancin, dalbavancin and oritavancin) are in advanced phase of clinical development. Similarly, new broad–spectrum cephalosporins active against MRSA (e.g. ceftobiprole and ceftaroline) and a new dihydrofolate reductase inhibitor (iclaprim) are in or have completed phase 3 studies.

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Implementation of a methicillin-resistant Staphylococcus aureus (MRSA) prevention bundle results in decreased MRSA surgical site infections
The American Journal of Surgery, 11/03/09 Relevance Score: 93%

Twenty-five year epidemiology of invasive methicillin-resistant Staphylococcus aureus (MRSA) isolates recovered at a burn center
Burns, 11/16/09 Relevance Score: 89%

Bench-to-bedside review: Understanding the impact of resistance and virulence factors on MRSA infections in the ICU
Critical Care, 10/27/09 Relevance Score: 88%

Clinical Importance of Purulence in Methicillin-Resistant Staphylococcus aureus Skin and Soft Tissue Infections
Journal of the American Board of Family Medicine, 11/09/09 Relevance Score: 87%

Enhanced surveillance of methicillin-resistant Staphylococcus aureus (MRSA) bacteraemia in children in the UK and Ireland
BMJ - Archives of Diseases in Childhood, 10/29/09 Relevance Score: 87%