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Predictors of Emesis and Recovery Agitation With Emergency Department Ketamine Sedation: An Individual-Patient Data Meta-Analysis of 8,282 Children
Annals of Emergency Medicine, 08/10/09
Green SM et al. – Early adolescence is the peak age for ketamine–associated emesis, and its rate is higher with IM administration and with unusually high IV doses. Recovery agitation is not age related to a clinically important degree. When the authors interpreted it in conjunction with the separate airway adverse event phase of this analysis, the authors found no apparent clinically important benefit or harm from coadministered anticholinergics and benzodiazepines and no increase in adverse events with either oropharyngeal procedures or the presence of substantial underlying illness.
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