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Can the ABCD2 risk score predict positive diagnostic testing for emergency department patients admitted for transient ischemic attack?
Stroke, 07/28/09
Schrock JW et al. – An elevated ABCD2 score may help predict pts with severe carotid occlusive disease but does not predict positive outcome in other commonly ordered tests for pts evaluated for transient ischemic attack. An elevated ABCD2 score cannot be recommended as a tool to guide diagnostic testing in pts presenting acutely with transient ischemic attack.
Methods- Study to determine if the ABCD2 score, typically used for risk stratification, could predict positive diagnostic test in pts evaluated acutely for transient ischemic attack
- Retrospective cohort study for pts admitted from emergency department with a new diagnosis of transient ischemic attack confirmed by a neurologist
- Calculation of ABCD2 scores
- High-risk cohort: pts with score of ≥4
- Tests evaluated: electrocardiogram, CT, MRI, MR angiography, carotid ultrasonography, echocardiography
- A priori determination of specific test findings considered to signify positive diagnostic tests
- Inclusion of 256 pts with transient ischemic attack: 167 (61%) female; median age 60 yrs; 162 (63%) pts had ABCD2 score ≥4
- Rates of completion of diagnostic testing: electrocardiogram, 270 (100%); CT, 224 (88%); MRI, 89 (35%); MR angiography, 68 (27%); carotid ultrasonography, 125 (49%); echocardiography, 135 (53%)
- On univariate analysis, significant association only with elevated ABCD2 score and carotid duplex testing
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