Emergency Med Medical News about mustard toxicity

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Chronic mustard toxicity on the testis: a historical cohort study two decades after exposure
International Journal of Andrology, 07/27/09

Amirzargar MA et al. – Testis histopathology of the azoospermic men showed complete absence of spermatogenesis with only Sertoli cells in the seminiferous tubules. SM can be gonadotoxic and its chronic toxicity may be permanent. Germ cells are probably the most susceptible gonadal cells to SM.

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Association of molecular markers with toxicity outcomes in a randomized trial of chemotherapy for advanced colorectal cancer: The FOCUS Trial
Journal of Clinical Oncology, 10/30/09 Relevance Score: 47%

Multicenter phase 2 study of belotecan, a new camptothecin analog, and cisplatin for chemotherapy-naive patients with extensive-disease small cell lung cancer
Cancer, 11/18/09 Relevance Score: 44%

The Successful Use of Intralipid for Treatment of Local Anesthetic-induced Central Nervous System Toxicity: Some Considerations for Administration of Intralipid in an Emergency
The Clinical Journal of Pain, 10/21/09 Relevance Score: 44%

The contribution of deleterious DPYD gene sequence variants to fluoropyrimidine toxicity in British cancer patients
Cancer Chemotherapy and Pharmacology, 10/07/09 Relevance Score: 44%

Fatal gemcitabine-induced pulmonary toxicity in metastatic gallbladder adenocarcinoma
Cancer Chemotherapy and Pharmacology, 11/18/09 Relevance Score: 43%