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The Relationship Between Homocysteine and Genes of Folate-Related Enzymes in Migraine Patients
Headache: The Journal of Head and Face Pain, 07/10/09
Oterino A et al. - These results suggest that MA patients have higher Hcy levels. The authors also observed complex epigenetic interaction among folate-related enzymes, sex, and Hcy levels predicting MA phenotype. Nevertheless, genetic factors explained only a minor proportion of the variance for both Hcy plasma levels and for predicting MA phenotype. Determination of MTHFR C677T polymorphisms and Hcy levels may be useful to identify patients with a high risk of suffering from MA.
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