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Preventing pain on injection of propofol: a comparison between peripheral ketamine pre-treatment and ketamine added to propofol
Anesthesia and Intensive Care, 07/06/09
The purpose of this study was to examine possible peripheral mechanisms for the reduction of propofol injection pain by the addition of ketamine. The results support pH changes as a more important cause for the decrease in propofol injection pain with the addition of ketamine to propofol than a peripheral effect of ketamine.
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