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Al-Chalabi A et al. - Based on the current literature, the commonly used systems, especially with regard to detoxification, seem to be useful in the treatment of patients with hepatic encephalopathy. At present, there is no evidence that treatment with the commercially available liver support systems can improve survival in patients with liver failure. Two large multi-center studies are being performed for MARS (Relief II) and Prometheus (Helios), which will hopefully answer these questions.


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