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Angiopoietin-2 in intensive care medicine
Intensivmedizin und Notfallmedizin, 06/25/09
Kümpers P et al. - Angiopoietin-2, the antagonistic ligand of the endothelial-specific Tie2 receptor, has been identified as a central mediator of endothelial activation in experimental sepsis. The concentration of angiopoietin-2 within the circulation is closely related to progressive organ dysfunction and mortality in critically ill patients.
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