Emergency Med Medical News about acute ischemic stroke; neurobiological processes

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The complexity of neurobiological processes in acute ischemic stroke
Clinical Neurology and Neurosurgery, 06/11/09

Brouns R et al. - In this review, the authors summarize the actual knowledge on the pathophysiology of acute ischemic stroke. The authors focus on the ischemic cascade, which is a complex series of neurochemical processes that are unleashed by transient or permanent focal cerebral ischemia and involves cellular bioenergetic failure, excitotoxicity, oxidative stress, blood–brain barrier dysfunction, microvascular injury, hemostatic activation, post-ischemic inflammation and finally cell death of neurons, glial and endothelial cells.

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Reperfusion Is a More Accurate Predictor of Follow-Up Infarct Volume Than Recanalization. A Proof of Concept Using CT in Acute Ischemic Stroke Patients
Stroke, 11/18/09 Relevance Score: 82%

Glucose Regulation in Acute Stroke Patients (GRASP) Trial. A Randomized Pilot Trial
Stroke, 10/27/09 Relevance Score: 81%

Significance of Large Vessel Intracranial Occlusion Causing Acute Ischemic Stroke and TIA
Stroke, 10/27/09 Relevance Score: 81%

Low Ankle-Brachial Index Predicts Cardiovascular Risk After Acute Ischemic Stroke or Transient Ischemic Attack
Stroke, 10/20/09 Relevance Score: 81%

Statin use before and after acute ischemic stroke onset improves neurological outcome
Expert Review of Cardiovascular Therapy, 10/19/09 Relevance Score: 81%