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Osteoarthritis in patients with anterior cruciate ligament rupture: A review of risk factors
The Knee, 06/10/09

Louboutin H et al. – Review outlines the risk factors for osteoarthritis (OA) in patients who sustain an anterior cruciate ligament (ACL) rupture. Although the principle arthrogenic factor is the increased anterior tibial displacement that is associated with the rupture, other direct and indirect factors also contribute.

Meniscal and chondral injuries can be present before, during, and develop after the index injury, making assessment difficult
Most studies concentrate on the radiological changes following ACL rupture and reconstruction
However the rate of significant symptomatic OA needing major surgical intervention is lower
This needs to be considered when advising pts on the management of their ruptured ACL
The long-term outcome in pts who are symptomatically stable following an ACL rupture is uncertain
Although in a small cohort of elite athletes all had degenerative changes by 35 yrs and 42% had undergone total knee replacement
At 20 yrs f/u the reported risk of developing OA is lower after ACL reconstruction

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