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See Latest ArticlesJAK mutations in high-risk childhood acute lymphoblastic leukemia
Proceedings of the National Academy of Sciences of the United States of America, 06/10/09
Mullighan CG et al. - The presence of JAK mutations was significantly associated with alteration of IKZF1 and deletion of CDKN2A/B. The JAK-mutated cases had a gene expression signature similar to BCR-ABL1 pediatric ALL, and they had a poor outcome. The results suggest that inhibition of JAK signaling is a logical target for therapeutic intervention in JAK mutated ALL.
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Thyroid lymphoma and airway obstruction – is there a rationale for surgical management?
International Journal of Clinical Practice, 10/19/09
Pegfilgrastim in children with severe congenital neutropenia
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Today in Pediatric Emergencies...keeping you current
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Management of acute appendicitis: an imaging strategy in children
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A Randomized Trial of Nebulized 3% Hypertonic Saline With Epinephrine in the Treatment of Acute Bronchiolitis in the Emergency Department
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