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See Latest ArticlesEntering the “triad of death” and the concept of futility in the use of recombinant activated factor VII
Injury Extra, 06/04/09
Phillips LE et al. - Despite laboratory data and clinical suggesting reduced efficacy with low pH and temperature, a surprising number of these patients were not only treated with rFVIIa but stopped bleeding and survived. Although clearly not ideal circumstances, these finding raise questions about the concept of futility in relation to rFVIIa treatment in major trauma.
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