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Sudden Death and Sickle Cell Trait: Medicolegal Considerations and Implications
American Journal of Forensic Medicine and Pathology, 06/01/09
Scheinin L et al. - Exercise-related collapse in persons with sickle cell trait is a rare but serious complication. It occurs most often in military recruits and deconditioned athletes undergoing intense physical training, but can also occur in other situations in which an individual exerts himself beyond his limits of endurance. Local hypoxia causes intravascular sickling, in turn causing vascular occlusion and organ and tissue damage.
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