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See Latest ArticlesIRF-1 Promotes Inflammation Early after Ischemic Acute Kidney Injury
Journal of the American Society of Nephrology, 05/15/09
Wang Y et al. - Acute renal ischemia elicits an inflammatory response that may exacerbate acute kidney injury, but the regulation of the initial signals that recruit leukocytes is not well understood. The data suggest that IRF-1 gene activation by reactive oxygen species is an early signal that promotes inflammation after ischemic renal injury.
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