Your Messages Inbox
Most Viewed Abstracts
1. Report Shows Shift in Starting Salaries for Physicians 2. Use of Antiemetic Agents in Acute Gastroenteritis 3. 2008 Exclusive Survey—Earnings: Good news for primary care income 4. Medicare pay-for-reporting effort draws fire from frustrated doctors 5. Debunking Myths in the US Healthcare System
Your Article Summary
See Latest ArticlesRandomized, double-blind, placebo-controlled, proof-of-concept study of the cortical spreading depression inhibiting agent tonabersat in migraine prophylaxis
Cephalalgia, 05/14/09
Goadsby PJ et al. - Tonabersat is a novel putative migraine prophylactic agent with an unique stereospecific binding site in the brain. Tonabersat has been shown, in animal models, to inhibit experimentally induced cortical spreading depression, the likely underlying mechanism for migraine aura, and cerebrovascular responses to trigeminal nerve stimulation. The aim was to study the potential for tonabersat as a migraine preventive. A randomized, double-blind, placebo-controlled, multicentre, parallel group study recruited patients with migraine with and without aura experiencing between two and six migraine attacks per month. After a 1-month baseline they received tonabersat 20 mg daily for 2 weeks and 40 mg daily for a further 10 weeks...The good tolerability and promising efficacy results support further exploration of higher doses of tonabersat in larger controlled trials.
Today in Neurology/Neurosurgery...keeping you current
Receive free subspecialty "5-minute updates" via email
Escitalopram and Venlafaxine for the Prophylaxis of Migraine Headache Without Mood Disorders
Clinical Neuropharmacology, 10/02/09
Stroke treatment with alteplase given 3·0—4·5 h after onset of acute ischaemic stroke (ECASS III): additional outcomes and subgroup analysis of a randomised controlled trial
The Lancet Neurology, 11/17/09
Safety and Efficacy of IV-TPA for Ischaemic Stroke in Clinical Practice - A Bayesian Analysis
Cerebrovascular Diseases, 10/30/09
Today in Pain Management...keeping you current
Receive free subspecialty "5-minute updates" via email
Escitalopram and Venlafaxine for the Prophylaxis of Migraine Headache Without Mood Disorders
Clinical Neuropharmacology, 10/02/09
Acute back pain: benefits and risks of current treatments
Current Medical Research and Opinion, 11/19/09
Migraine Chronification - Concept and Risk Factors
Discovery Medicine, 10/27/09
Today in Preventive Medicine...keeping you current
Receive free subspecialty "5-minute updates" via email
Escitalopram and Venlafaxine for the Prophylaxis of Migraine Headache Without Mood Disorders
Clinical Neuropharmacology, 10/02/09
Prevention of episodic migraines with topiramate: results from a non-interventional study in a general practice setting
The Journal of Headache and Pain, 11/10/09
Pandemic preparedness - Risk management and infection control for all respiratory infection outbreaks
Australian Family Physician, 11/09/09
Article Search
Sponsor