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Telmisartan in migraine prophylaxis: a randomized, placebo-controlled trial
Cephalalgia, 05/14/09
Diener HC et al. - The authors evaluated telmisartan 80 mg for migraine prophylaxis. Migraine patients (n = 95) with three to seven migraine attacks in 3 months were randomized, double-blind to telmisartan or placebo...The reduction in migraine days was 1.65 with telmisartan and 1.14 with placebo. Post hoc analyses adjusting for baseline and centre showed a 38% reduction in migraine days with telmisartan vs. 15% with placebo, and a borderline significant difference in responders. The incidence of adverse events was similar between treatments. This study indicates that telmisartan might be effective in migraine prophylaxis.
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