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Decima D et al. - The authors describe a 41-year-old man, in good health, with MA since 16, familiar history of diabetes, heavy smoker (30 cigarettes/day). Frequency (1–2 attacks/year) and clinical features of migraine have been unchanged since the onset. A few days before the authors examination he suffered a typical migraine attack. In the following hours, however, the headache became more and more throbbing and the aura symptoms (regressed as usual in 30 min) reappeared and persisted, so he went to an Emergency Department. The CT-scan (without contrast) was normal. The following days he had visual disturbances and spatial disorientation. The authors found a normal neurological examination and fundus oculi. He referred persisting visual troubles. The authors prescribed MR + angioMR which confirmed a migrainous infarction and ruled out others pathological conditions. Further tests found out dislipidemia, hyperhomocysteinemia, impaired glucose tolerance. Transcranial Doppler showed right to left shunting.

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