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See Latest ArticlesBiomarkers of Blast-Induced Neurotrauma: Profiling Molecular and Cellular Mechanisms of Blast Brain Injury
Journal of Neurotrauma, 05/08/09
Svetlov SI et al. - The nature of warfare in the 21st century has led to a significant increase in primary blast or over-pressurization injuries to the whole body and head, which manifest as a complex of neuro-somatic damage, including traumatic brain injury (TBI). Identifying relevant pathogenic pathways in reproducible experimental models of primary blast wave exposure is therefore vital to the development of biomarkers for diagnostics of blast brain injury. Comparative analysis of mechanisms and putative biomarkers of blast brain injury is complicated by a deficiency of experimental studies. In this article, the authors present an overview of current TBI biomarkers, as well as outline experimental strategies to investigate molecular signatures of blast neurotrauma and to develop a pathway network map for novel biomarker discovery. These biomarkers will be effective for triaging and managing both combat and civilian causalities.
Today in Basic Science...keeping you current
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Inhibition of NF-kB ameliorates sepsis-induced downregulation of aquaporin-2 / V2 receptor expression and acute renal failure in vivo
American Journal of Physiology: Renal Physiology, 10/15/09
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Pandemic (H1N1) 2009 influenza: experience from the critical care unit
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Federal Declaration of a Public Health Emergency
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Escitalopram and Venlafaxine for the Prophylaxis of Migraine Headache Without Mood Disorders
Clinical Neuropharmacology, 10/02/09
Migraine Chronification - Concept and Risk Factors
Discovery Medicine, 10/27/09
Safety and Efficacy of IV-TPA for Ischaemic Stroke in Clinical Practice - A Bayesian Analysis
Cerebrovascular Diseases, 10/30/09
Today in Trauma...keeping you current
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Use of intra-articular lidocaine as analgesia in anterior shoulder dislocation: a review and meta-analysis of the literature
Canadian Journal of Rural Medicine, 10/22/09
Nonoperative Management of Blunt Abdominal Trauma: Have We Gone Too Far
Surgical Infections, 11/02/09
Management of mammalian bites
Australian Family Physician, 11/06/09
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