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Shakuyaku-kanzo-to Induces Pseudoaldosteronism Characterized by Hypokalemia, Rhabdomyolysis, Metabolic Alkalosis with Respiratory Compensation, and Increased Urinary Cortisol Levels
Journal of Alternative and Complementary Medicine, 04/28/09
Kinoshita H et al. - In this case, the observed reduction in the urinary cortisol levels, from 600.6 to 37.8microg/day, led to a definitive diagnosis of pseudoaldosteronism instead of the apparent mineralocorticoid excess syndrome. Discontinuing shakuyaku-kanzo-to treatment and administering spironolactone and potassium proved effective in improving the patient's condition. Medical practitioners prescribing shakuyaku-kanzo-to should take into account the association between licorice, which is its main ingredient, and pseudoaldosteronism.
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