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Can extremely low or high morphine formation from codeine be predicted prior to therapy initiation?
Pain, 04/27/09
Lotsch J et al. - Insufficient morphine formation from codeine and thus likely failure of analgesia can currently be well predicted. However, to make codeine therapy safe, extremely high morphine formation has to be predicted as well, which has to be obtained at the effort of combining genotyping with phenotyping.
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