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See Latest ArticlesAcute effects of peritoneal dialysis solutions in the mesenteric microcirculation
Translational Research, The Journal of Laboratory and Clinical Medicine, 04/27/09
Frajewicki V et al. - Exposure to glucose 3.86% bicarbonate buffered (Physioneal) solution was associated with the lowest values of leukocyte rolling and adhesion among the PD solutions and with extremely higher venular flow velocities and shear rates. A single exposure to conventional PD solutions with a high concentration of glucose or polyglucose (Icodextrin 7.5%) induces changes consistent with an early peritoneal inflammatory response that may be attenuated by the use of bicarbonate-based fluids.
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