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Insulin Analogs versus Human Insulin in the Treatment of Patients with Diabetic Ketoacidosis
Diabetes Care, 04/22/09
Umpierrez GE et al. - Regular and glulisine insulin are equally effective during the acute treatment of DKA. Transition to SC glargine and glulisine following resolution of DKA resulted in similar glycemic control but in a lower rate of hypoglycemia than NPH and regular insulin. Thus, a basal bolus regimen with glargine and glulisine is safer and should be preferred over NPH and regular insulin following the resolution of DKA.
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