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See Latest ArticlesIs there a therapeutic window with some antidepressants for analgesic response
Current Pain and Headache Reports, 03/19/09
Atkinson JH et al. - Most antidepressants and anticonvulsants used in chronic pain syndromes have dose- and concentration-response curves developed for their application to treat psychiatric disorders. Because these are important clinical tools in medication management of psychiatric syndromes, it is reasonable to expect that utilizing concentration-effect relationships and known sources of pharmacokinetic variability for determining doses for analgesia may also improve treatment tolerability and outcomes.
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