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See Latest ArticlesSumatriptan does not change calcitonin gene-related peptide in the cephalic and extracephalic circulation in healthy volunteers
The Journal of Headache and Pain, 03/10/09
Hansen JM et al. - It was found that Sumatriptan did not change the levels of circulating CGRP in the intra or extracerebral circulation in healthy volunteers. This speaks against a direct CGRP-reducing effect of sumatriptan in vivo in humans when the trigemino vascular system is not activated.
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