Emergency Med Medical News about acutely ill older medical inpatients; Cytokines; IGF-I

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Cytokines and IGF-I in delirious and non-delirious acutely ill older medical inpatients
Age and Aging, 03/10/09

Adamis D et al. - This study finds that (i) low levels of both neuroprotective factors (IGF-I, IL-1RA) are associated with delirium, (ii) high IFN-gamma and low IGF-I have significant effects on delirium severity and (iii) otherwise the pro-inflammatory cytokines studied, APOE genotype and severity of illness do not appear to be associated, in older medically ill patients, with either delirium or severity of it.

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