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Endotoxin causes pulmonary hypertension by upregulating smooth muscle endothelin type-b receptors: role of aldose reductase
Shock, 07/18/08
Dschietzig T et al. - Endotoxin-induced pulmonary hypertension in the rat results from a loss of endothelial and concomitant gain of vascular smooth muscle ETB receptors. These changes are at least partly mediated by aldose reductase.
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