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See Latest ArticlesUpdate on the role of nonsteroidal anti-inflammatory drugs and coxibs in the management of acute pain
Current Opinion in Anesthesiology, 09/20/07
Reuben, S.S., et al. - Although NSAIDs have been shown to reduce postoperative analgesics, their ability to reduce opioid-related adverse effects and improve functional outcomes is questioned. Further, perioperative NSAID use may contribute to cardiovascular toxicity and impaired bone healing. This review highlights recent advances in our understanding of the role perioperative NSAIDs have on modulating nociception, their benefits when utilized as components of a multimodal analgesic regimen, and potential deleterious cardiovascular and osteogenic effects
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