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Emergency Medicine - Clinical Pharmacology News & Articles

MDLinx.com is your one stop shop for the latest Emergency Medicine news articles and peer reviewed clinical journal articles categorized daily into various hot topics such as: Trauma, Emergency Medicine Services, Airway/Respiratory management, Toxicology and much more. Not only are we the quickest, writing summaries of every article with 24 hours of publication, but we are also your most efficient resource for up-to-the-minute literature in Emergency Medicine.

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Your Unread Messages in Emergency Medicine

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Articles

Latest Full Text Articles (39)
Ranked, sorted, and summarized by MDLinx editors from the latest literature
Topics:

121 Risk Factors and Outcomes of Carbapenem-resistant Acinetobacter baumannii Bacteremia in Neonatal Intensive Care Unit: A Case-case-control Study The Pediatric Infectious Disease Journal, January 23, 2013    Clinical Article

122 Age-related Differences in Propofol Dosing for Procedural Sedation in the Emergency Department The Journal of Emergency Medicine, January 21, 2013    Clinical Article

123 Analgesic response to morphine in obese and morbidly obese patients in the emergency department Emergency Medicine Journal, January 18, 2013    Clinical Article

124 Evaluation of discontinuation of atypical antipsychotics prescribed for icu delirium Journal of Pharmacy Practice, January 17, 2013    Clinical Article

125 Acute Cervical Dystonia After the First Dose of Butamirate Citrate Pediatric Emergency Care, January 15, 2013    Clinical Article

126 Phenotypic detection of Klebsiella pneumoniae carbapenemase among burns patients: First report from Iran Burns, January 11, 2013    Review Article    Clinical Article

127 Antifibrinolytic drugs for acute traumatic injury Cochrane Reviews, January 10, 2013    Clinical Article

128 High-dose norepinephrine treatment: determinants of mortality and futility in critically ill patients American Journal of Critical Care, January 10, 2013    Clinical Article

129 Emergency Department Vancomycin Use: Dosing Practices and Associated Outcomes The Journal of Emergency Medicine, January 9, 2013    Clinical Article

130 Colistin in burn intensive care: Back to the future? Burns, January 9, 2013    Clinical Article

131 A four arm, double blind, randomized and placebo controlled study of pregabalin in the management of post-burn pruritus Burns, January 8, 2013    Clinical Article

132 Antibiotic surveillance on a paediatric intensive care unit: easy attainable strategy at low costs and resources Full Text BMC Pediatrics, January 8, 2013    Review Article

133 Intravenous Hypertonic Saline Use in the Pediatric Emergency Department Pediatric Emergency Care, January 7, 2013    Clinical Article

134 Barbiturates for acute traumatic brain injury Cochrane Reviews, January 4, 2013    Clinical Article

135 Serelaxin, recombinant human relaxin-2, for treatment of acute heart failure (RELAX-AHF): a randomised, placebo-controlled trial The Lancet, January 4, 2013    Clinical Article

136 The Efficacy of Gabapentin and Pregabalin in the Treatment of Neuropathic Pain due to Peripheral Nerve Injury Journal of Musculoskeletal Pain , January 2, 2013

137 5% Lidocaine Medicated Plaster Use in Children with Neuropathic Pain from Burn Sequelae Pain Medicine, January 2, 2013    Clinical Article

138 Parental Preference for Short- Versus Long-Course Corticosteroid Therapy in Children With Asthma Presenting to the Pediatric Emergency Department Clinical Pediatrics, December 21, 2012    Clinical Article

139 Windmills and Pill Mills: Can PDMPs Tilt the Prescription Drug Epidemic? Journal of Medical Toxicology, December 20, 2012

140 Sequential azacitidine plus lenalidomide combination for elderly patients with untreated acute myeloid leukemia Full Text Haematologica, December 19, 2012    Clinical Article

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Clinical Pearls in Emergency Medicine

Highlights in Emergency Medicine

Procalcitonin and CRP predict identify high-risk children with appendicitis

As published in Pediatric Emergency Care, procalcitonin and CRP levels discriminate between children admitted with a diagnosis of acute appendicitis who may require closer monitoring. The study involved 111 children who were divided into 2 groups based on intra-operative diagnoses of appendicitis (n=69) and peritonitis (n=42). Patients with peritonitis, who were more likely to have complications and require intensive care unit admission, had significantly higher procalcitonin (0.15 vs. 4.95 ng/ml) and CRP levels (3 vs. 14.3 mg/dl) on admission than patients with appendicitis. Using a cut-off procalcitonin level of 0.18 ng/ml, the sensitivity, specificity, positive predictive value, and negative predictive value for peritonitis were 97%, 80%, 72%, and 89.3%, respectively. Using a cut-off CRP level of 3 mg/dl, the sensitivity, specificity, positive predictive value, and negative predictive value for peritonitis were 95%, 74%, 68%, and 96.2%, respectively.

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Vomiting during acute stroke increases mortality

As published in the Emergency Medicine Journal, patients who vomit during acute strokes have an increased risk of mortality (HR=5.06). Of 1968 stroke patients enrolled in the study, 1349 had cerebral infarctions, 459 had cerebral hemorrhages, and 152 had subarachnoid hemorrhages; 14.5% of all stroke patients vomited during the acute stage of the stroke (cerebral infarction, 8.7%; cerebral hemorrhage, 23.7%; and subarachnoid hemorrhage, 36.8%).

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Association between tight glycemic control and hip fracture in diabetics

As published in the Journal of the American Geriatrics Society, patients with T2DM (mean age, 77.3 y; n=932) with a HbA1c < 6% (OR=3.01) or 6.1-7% (OR=2.34) are more likely to sustain a hip fracture than patients with a HbA1c > 8%. All patients had a HbA1c level determined within 3 months preceding the hip fracture. No differences in risk existed between patients treated with oral hypoglycemics or insulin.

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Most Popular Emergency Medicine Articles

Last month's top read Top Articles of 2012

1 Oxycodone Versus Codeine for Triage Pain in Children With Suspected Forearm Fracture: A Randomized Controlled Trial Pediatric Emergency Care, March 14, 2013

2 Mortality and morbidity after high-dose methylprednisolone treatment in patients with acute cervical spinal cord injury: a propensity-matched analysis using a nationwide administrative database Emergency Medicine Journal, March 11, 2013

3 Early analgesic treatment regimens for patients with acute abdominal pain: a nationwide survey among general surgeons Langenbeck's Archives of Surgery, March 4, 2013

4 Parenteral Fish Oil Lipid Emulsions in the Critically Ill: A Systematic Review and Meta-Analysis Journal of Parenteral and Enteral Nutrition, April 29, 2013    Evidence Based Medicine    Review Article

5 Time to First Antibiotics for Pneumonia is not Associated with In-Hospital Mortality The Journal of Emergency Medicine, March 4, 2013    Review Article

6 Topical Analgesics in the Management of Acute and Chronic Pain Mayo Clinic Proceedings, February 20, 2013    Review Article

7 Pharmacokinetics of Doripenem in Infected Patients Treated Within and Outside the Intensive Care Unit Annals of Pharmacotherapy, April 22, 2013

8 Role of dexmedetomidine in adults in the intensive care unit: An update American Journal of Health-System Pharmacy, April 24, 2013

9 Continuous versus intermittent infusions of antibiotics for the treatment of severe acute infections Cochrane Reviews, April 15, 2013    Review Article

10 Safety and Efficacy of Intravenous Hypotonic 0.225% Sodium Chloride Infusion for the Treatment of Hypernatremia in Critically Ill Patients Nutrition in Clinical Practice, April 24, 2013

11 Randomized Clinical Trial of Efficacy and Safety of a Single 2-mg Intravenous Dose of Hydromorphone Versus Usual Care in the Management of Acute Pain Academic Emergency Medicine, February 18, 2013

12 Time to antibiotics for septic shock: evaluating a proposed performance measure The American Journal of Emergency Medicine, February 11, 2013

13 Risk of Traumatic Intracranial Hemorrhage In Patients With Head Injury and Preinjury Warfarin or Clopidogrel Use Academic Emergency Medicine, February 14, 2013

14 Risks and Benefits Associated With Antibiotic Use for Acute Respiratory Infections: A Cohort Study Annals of Family Medicine, March 22, 2013    Free full text

15 Acute encephalopathy with concurrent respiratory and metabolic disturbances in first known parenteral human administration of flunixin meglumine and acepromazine maleate The Journal of Emergency Medicine, March 28, 2013

16 Hemorrhagic Complications in Emergency Department Patients Who Are Receiving Dabigatran Compared With Warfarin Annals of Emergency Medicine, April 16, 2013

17 Review of Recently Approved Alternatives to Anticoagulation with Warfarin for Emergency Clinicians The Journal of Emergency Medicine, February 4, 2013    Review Article

18 Treatment with an Oxazolidinone Antibiotic Inhibits Toxic Shock Syndrome Toxin-1 Production in MRSA-Infected Burn Wounds Journal of Burn Care & Research, April 2, 2013    Review Article

19 Administration of metoclopramide by infusion or bolus does not affect the incidence of drug-induced akathisia Emergency Medicine Australasia, April 10, 2013

20 Low-Dose Anticoagulation for Secondary Prevention in Acute Coronary Syndrome The American Journal of Cardiology, February 22, 2013

Indexed Journals in Emergency Medicine: Journal of Emergency Medicine, Annals of Emergency Medicine, Injurymore

Other Topics in Emergency Medicine

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