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Emergency Medicine - Clinical Pharmacology News & Articles
MDLinx.com is your one stop shop for the latest Emergency Medicine news articles and peer reviewed clinical journal articles categorized daily into various hot topics such as: Trauma, Emergency Medicine Services, Airway/Respiratory management, Toxicology and much more. Not only are we the quickest, writing summaries of every article with 24 hours of publication, but we are also your most efficient resource for up-to-the-minute literature in Emergency Medicine.
As an added feature, on this page you can also view highly recommended articles highlighted by our physician editor D. Scott Cunningham, MD, PhD and clinical pearls from the Internal Medicine Physician Review.
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Your Unread Messages in Emergency Medicine
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Mortality rate less in obese patients with sepsis
Articles
Latest Full Text Articles (39)41 Methylene Blue for Distributive Shock: A Potential New Use of an Old Antidote Journal of Medical Toxicology, April 15, 2013 Clinical Article
42 Comparison of Prasugrel and Ticagrelor Loading Doses in ST-Segment Elevation Myocardial Infarction Patients RAPID (Rapid Activity of Platelet Inhibitor Drugs) Primary PCI Study JACC - Journal of the American College of Cardiology, April 12, 2013 Clinical Article
43 A meta-analysis of analgesic and sedative effects of dexmedetomidine in burn patients Burns, April 12, 2013 Clinical Article
44 Topical ozonated oil versus hyaluronic gel for the treatment of partial- to full-thickness second-degree burns: A prospective, comparative, single-blind, non-randomised, controlled clinical trial Burns, April 11, 2013 Review Article
45 Efficacy of debridement and wound cleansing with 2% hydrogen peroxide on graft take in the chronic-colonized burn wounds; a randomized controlled clinical trial Burns, April 11, 2013 Clinical Article
46 De-escalation of antimicrobial treatment for adults with sepsis, severe sepsis or septic shock Cochrane Reviews, April 11, 2013 Review Article
47 Administration of metoclopramide by infusion or bolus does not affect the incidence of drug-induced akathisia Emergency Medicine Australasia, April 10, 2013 Clinical Article
48 Proton Pump Inhibitors and Risk of 1-Year Mortality and Rehospitalization in Older Patients Discharged From Acute Care Hospitals Proton Pump Inhibitors in Older Patients JAMA Internal Medicine, April 10, 2013 Clinical Article
49 A Randomized Trial of Intravenous Ketorolac Versus Intravenous Metoclopramide Plus Diphenhydramine for Tension-Type and All Nonmigraine, Noncluster Recurrent Headaches Annals of Emergency Medicine, April 9, 2013 Clinical Article
50 Recombinant Activated Factor VII Use in Critically Ill Patients: Clinical Outcomes and Thromboembolic Events Annals of Pharmacotherapy, April 9, 2013 Review Article
51 Development of Pyloric Stenosis After a 4-Day Course of Oral Erythromycin Pediatric Emergency Care, April 9, 2013
52 Effect of Platelet Inhibition with Cangrelor during PCI on Ischemic Events New England Journal of Medicine, April 8, 2013 Clinical Article
53 Skin Hypersensitivity to Sun Light Due to Doxycycline Ingestion Causing Hand Partial-Thickness Burn The Journal of the American College of Clinical Wound Specialists, April 5, 2013 Clinical Article
54 A comparative study of 1% silver sulphadiazine (Flammazine) versus an enzyme alginogel (Flaminal) in the treatment of partial thickness burns Burns, April 4, 2013 Clinical Article
55 A descriptive study of myoclonus associated with etomidate procedural sedation in the ED The American Journal of Emergency Medicine, April 4, 2013 Clinical Article
56 Population distribution of methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C risk alleles for methotrexate toxicity in Israel Rheumatology International, April 4, 2013 Clinical Article
57 Treatment with an Oxazolidinone Antibiotic Inhibits Toxic Shock Syndrome Toxin-1 Production in MRSA-Infected Burn Wounds Journal of Burn Care & Research, April 2, 2013 Review Article
58 Thromboprophylaxis for trauma patients Cochrane Reviews, April 1, 2013 Review Article
59 Statins of high versus low cholesterol-lowering efficacy and the development of severe renal failure Pharmacoepidemiology and Drug Safety, March 29, 2013 Clinical Article
60 Acute encephalopathy with concurrent respiratory and metabolic disturbances in first known parenteral human administration of flunixin meglumine and acepromazine maleate The Journal of Emergency Medicine, March 28, 2013
Clinical Pearls in Emergency Medicine
- Appendicitis is the most common pediatric gastrointestinal surgical emergency.
- Drug-eluting stent (DES) placement improves revascularization rates without increased 3-year hazard of adverse clinical outcomes among individuals undergoing emergency primary percutaneous coronary intervention due to ST-segment elevation myocardial infarctions (STEMIs).
- Using an accelerated diagnostic protocol (ADP) with Troponin 1 as the sole biomarker may successfully identify low short-term risk of major adverse coronary event (MACE), and decrease observation time among individuals who present to the ER with chest pain.
Highlights in Emergency Medicine
Procalcitonin and CRP predict identify high-risk children with appendicitis
As published in Pediatric Emergency Care, procalcitonin and CRP levels discriminate between children admitted with a diagnosis of acute appendicitis who may require closer monitoring. The study involved 111 children who were divided into 2 groups based on intra-operative diagnoses of appendicitis (n=69) and peritonitis (n=42). Patients with peritonitis, who were more likely to have complications and require intensive care unit admission, had significantly higher procalcitonin (0.15 vs. 4.95 ng/ml) and CRP levels (3 vs. 14.3 mg/dl) on admission than patients with appendicitis. Using a cut-off procalcitonin level of 0.18 ng/ml, the sensitivity, specificity, positive predictive value, and negative predictive value for peritonitis were 97%, 80%, 72%, and 89.3%, respectively. Using a cut-off CRP level of 3 mg/dl, the sensitivity, specificity, positive predictive value, and negative predictive value for peritonitis were 95%, 74%, 68%, and 96.2%, respectively.
Read the article summaryVomiting during acute stroke increases mortality
As published in the Emergency Medicine Journal, patients who vomit during acute strokes have an increased risk of mortality (HR=5.06). Of 1968 stroke patients enrolled in the study, 1349 had cerebral infarctions, 459 had cerebral hemorrhages, and 152 had subarachnoid hemorrhages; 14.5% of all stroke patients vomited during the acute stage of the stroke (cerebral infarction, 8.7%; cerebral hemorrhage, 23.7%; and subarachnoid hemorrhage, 36.8%).
Read the article summaryAssociation between tight glycemic control and hip fracture in diabetics
As published in the Journal of the American Geriatrics Society, patients with T2DM (mean age, 77.3 y; n=932) with a HbA1c < 6% (OR=3.01) or 6.1-7% (OR=2.34) are more likely to sustain a hip fracture than patients with a HbA1c > 8%. All patients had a HbA1c level determined within 3 months preceding the hip fracture. No differences in risk existed between patients treated with oral hypoglycemics or insulin.
Read the article summaryMost Popular Emergency Medicine Articles
Last month's top read Top Articles of 2012Indexed Journals in Emergency Medicine: Journal of Emergency Medicine, Annals of Emergency Medicine, Injury more
Other Topics in Emergency Medicine
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