Out-of-hospital Cardiac Arrest Outcomes Stratified By Rhythm Analysis
Mader TJ et al. – After out–of–hospital cardiac arrest (OHCA), the survival rate for CS victims is significantly lower than for IS patients. These findings suggest that initial shockable (IS) and converted shockable (CS) are different entities and that alternatives to existing resuscitation algorithm tailored to patients with CS should be investigated.Methods
- The study was IRB approved.
- All adult index events at participating sites (2005-2010) were study eligible.
- All patient data elements were provided.
- Odds ratios of CS and NS status for survival to hospital discharge were calculated via multivariate logistic regression that adjusted for demographics, site, resuscitation initiators, AED use, and other covariates.
- There were 40,274 OHCA records submitted to the CARES registry during the study period.
- After exclusions, the final sample size was 30,939 (7,404 IS [23.9%], 3,225 CS [10.4%], 20,310NS [65.7%]).
- Raw survival rates of CS and NS patients were similar (4.7% vs. 4.1% respectively; p=0.08) but significantly lower than IS patients (26.9%; p<0.001).
- The adjusted OR of survival to hospital discharge for CS was 0.17 (95%CI: 0.14, 0.20) and for NS it was 0.17 (95%CI: 0.15, 0.18) with IS as the referent.