Maternal outcomes in critically ill obstetrics patients: A unique challenge

Indian Journal of Critical Care Medicine, 03/30/2012

Bhadade R et al. – The findings suggest that prompt treatment with oseltamivir in H1N1 infection was associated with good maternal and fetal outcomes.


  • It is a prospective observational study, carried out in the MICU of a tertiary care teaching hospital over a period of 18months.
  • One hundred and twenty-two pregnant and postpartum females (up to 42days after delivery) were studied.


  • Maternal age >30 years was associated with high mortality (68.2%).
  • Majority of the females were admitted in the third trimester (50 patients) and postpartum period (41 patients), and mortality was highest in the postpartum period (39%).
  • Increasing parity and gravida was associated with significantly high mortality (59.5%).
  • Acute viral hepatitis E (45 patients) was most common indication for MICU transfer, followed by malaria and pregnancy-induced hypertension.
  • The mortality rate was 30.3%.
  • The most common cause of death was acute viral hepatitis E (24 patients), with hepatic failure (53 patients) being the most common organ failure.
  • Majority of the females (88 patients) were ANC registered.
  • Low Glasgow coma score and high APACHE II score on admission were associated with significantly high mortality (85.2%).

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