Maternal outcomes in critically ill obstetrics patients: A unique challenge
Indian Journal of Critical Care Medicine, 03/30/2012
Bhadade R et al. – The findings suggest that prompt treatment with oseltamivir in H1N1 infection was associated with good maternal and fetal outcomes.
It is a prospective observational study, carried out in the MICU of a tertiary care teaching hospital over a period of 18months.
One hundred and twenty-two pregnant and postpartum females (up to 42days after delivery) were studied.
Maternal age >30 years was associated with high mortality (68.2%).
Majority of the females were admitted in the third trimester (50 patients) and postpartum period (41 patients), and mortality was highest in the postpartum period (39%).
Increasing parity and gravida was associated with significantly high mortality (59.5%).
Acute viral hepatitis E (45 patients) was most common indication for MICU transfer, followed by malaria and pregnancy-induced hypertension.
The mortality rate was 30.3%.
The most common cause of death was acute viral hepatitis E (24 patients), with hepatic failure (53 patients) being the most common organ failure.
Majority of the females (88 patients) were ANC registered.
Low Glasgow coma score and high APACHE II score on admission were associated with significantly high mortality (85.2%).