Euglycaemic ketoacidosis in patients with and without diabetes
Practical Diabetes, May 16, 2013
Le Neveu F et al. - The aim of this review is to compare the clinical features, pathophysiology and management of these conditions. Common clinical features due to a raised anion gap metabolic acidosis are seen. Reduced carbohydrate intake is a usual contributor to ketogenesis. Treatment is primarily with intravenous glucose, insulin if there is insulin deficiency and potassium as needed. The value of using bedside monitors to measure β-hydroxybutyrate levels both for ...
Diabetic ketoacidosis at the onset of type 1 diabetes is associated with future HbA1c levels
Diabetologia - Clinical and Experimental Diabetes and Metabolism, April 16, 2013
Fredheim S et al. – The authors investigated the long–term impact of diabetic ketoacidosis (DKA) at onset on metabolic regulation and residual beta cell function in a Danish population with type 1 diabetes. DKA at diagnosis was associated with poor long–term metabolic regulation and residual beta cell function as assessed by HbA 1c and IDAA 1c , respectively; however, CSII treatment was associated with improvement in glycaemic regulation and residual beta cell function, changing the effect ...
Clinical characteristics and insulin-independency of new-onset Korean type 2 diabetics presenting with diabetic ketoacidosis
Diabetes/Metabolism Research and Reviews, May 9, 2013
Seok H et al. - The authors evaluated the incidence, characteristics, and insulin-independency of newly diagnosed Korean type 2 diabetes (T2D) initially presenting with diabetic ketoacidosis (DKA). New-onset T2D presenting with DKA was not uncommon among the Korean population. In contrast to previously-diagnosed T2D patients presenting with DKA who showed a progressive decrease in insulin secretory function, new-onset KPD-T2B patients recovered insulin ...
Ketoacidosis as the initial clinical condition in nine patients with acromegaly: A review of 860 cases at a single institute
European Journal of Endocrinology, May 9, 2013
Yoshida N et al. - Excess growth hormone (GH) causes insulin resistance and impaired glucose metabolism. The objective of this study was to clarify the prevalence of ketoacidosis as the initial presenting symptom of acromegaly. Approximately 1% of patients with acromegaly presented with diabetic ketoacidosis as their first clinical condition.
Maternal depressive symptoms predict acute hospitalization among children with type 1 diabetes
Pediatric Diabetes, February 14, 2013
Butwicka A et al. – The aim of this study is to examine the impact of a mother's depressive symptoms on the risk of hospital admission of her child due to severe hypoglycemia or diabetic ketoacidosis. Children with T1DM whose mothers show high level of depressive symptoms are at an elevated risk for hospitalization due to acute diabetic complication. Methods One hundred sixty-six mothers of children with type 1 diabetes (T1DM) were evaluated using the Hamilton Depression Rating Scale ...