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Salix Pharmaceuticals, Ltd. announced the successful outcome of two Phase 3, randomized, double–blind, placebo–controlled, multicenter trials, TARGET 1 and TARGET 2, designed to evaluate the efficacy and safety of rifaximin 550 mg TID in the treatment of patients with non–constipation irritable bowel syndrome. In each trial rifaximin versus placebo treated patients demonstrated a statistically significant improvement for the primary endpoint of the adequate relief of IBS symptoms as assessed over one month following completion of a 14–day course of therapy.

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