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ISENTRESS, an integrase inhibitor from Merck & Co., Inc., was studied in comparison to efavirenz in maintaining viral load suppression to undetectable levels and at improving CD4 cell counts in previously untreated HIV–1–infected patients through 96 weeks in a Phase III study called STARTMRK. In STARTMRK, ISENTRESS patients received either ISENTRESS or efavirenz in combination therapy. The data was presented at the 49th Interscience Conference on Antimicrobial Agents and Chemotherapy in San Francisco, CA.

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