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Preparation and characterization of marine sponge collagen nanoparticles and employment for the transdermal delivery of 17 beta-estradiol-hemihydrate
Drug Development and Industrial Pharmacy, 08/19/09

Nicklas M et al. – The hydrogel with estradiol–loaded collagen nanoparticles enabled a prolonged estradiol release compared to a commercial gel and yielded a considerably enhanced estradiol absorption. Consequently, sponge collagen nanoparticles represent promising carriers for transdermal drug delivery.

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