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Economic analysis of alvimopan in North American Phase III efficacy trials
American Journal of Health-System Pharmacy, 07/28/09
Bell TJ et al. – In a post hoc analysis, alvimopan was associated with significantly faster upper and lower GI recovery after bowel resection and a mean LOS reduction of one day compared with placebo. The mean estimated hospital cost was $879–$977 less for patients who received alvimopan compared with placebo. The base–case and sensitivity analyses suggest that, on average, the use of alvimopan compared with placebo may have a cost–saving effect in the hospital setting.
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