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Systematic Evaluation of Drug-Disease Relationships to Identify Leads for Novel Drug Uses
Clinical Pharmacology & Therapeutics, 07/02/09

Chiang AP et al. - The authros systematically evaluated a drug treatment–based view of diseases in order to address this challenge. Suggestions for novel drug uses were generated using a "guilt by association" approach. When compared with a control group of drug uses, the suggested novel drug uses generated by this approach were significantly enriched with respect to previous and ongoing clinical trials.

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