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Certolizumab pegol (Cimzia): Anti-TNF-alpha mAb approved for the treatment of rheumatoid arthritis
Formulary , 06/10/09
Tumor necrosis factor (TNF)-alpha is a proinflammatory cytokine that plays a key role in inflammatory processes. Certolizumab is a humanized monoclonal antibody (mAb) that neutralizes TNF-alpha. This agent was approved on May 2009, for the treatment of adults with moderately to severely active rheumatoid arthritis.
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