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The importance of an extra loop in the B-domain of an alpha-amylase from B. stearothermophilus US100
Biochemical and Biophysical Research Communications, 06/12/09
Khemakhem B et al. - The structural investigation showed that stabilizing deletions contribute to reinforce the architecture of domain B and the active site conformation. The deletion of three residues reduces the flexibility of this region and abolishes a denser hydrogen bond network.
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Position statement of the Portuguese Society of Nephrology on the clinical use of biotechnological drugs in renal patients
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