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RYZOLT is now available from Purdue Pharma L.P. for the management of moderate to moderately severe chronic pain in adults who require around-the-clock treatment of their pain for an extended period of time. RYZOLT's active ingredient, tramadol, is a centrally-acting synthetic opioid analgesic that binds to the µ -opioid receptor and also inhibits the reuptake of both serotonin and norepinephrine. Taken once every 24 hours, RYZOLT offers convenient dosing in 100 mg, 200 mg, and 300 mg tablet strengths. Eligible patients prescribed RYZOLT may receive a special RYZOLT Patient Value Card from their physician that can be applied at the pharmacy for immediate value of up to 14 days of RYZOLT, and extended value of up to $35 dollars off their out-of-pocket costs for each prescription filled, until December 20101.

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