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Application of Overall Equipment Effectiveness to Biopharmaceutical Manufacturing
BioPharm, 05/14/09

Already being actively followed by several industries, the overall equipment effectiveness approach quantifies the percentage of time that equipment operates to produce an acceptable product. It measures how effectively machines are being used by examining productivity and performance diagnostics at the equipment level.1, It also monitors actual performance relative to performance capabilities under optimal manufacturing conditions. OEE breaks down non-operable time into shutdown losses, operational downtime, changeover downtime, equipment failure, process failure, and production adjustment losses, which then are measured to calculate availability, performance, and quality losses.

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