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See Latest ArticlesActive Biotech presents S100A9 as a target for quinoline compounds
Active Biotech, 04/29/09
In this study it is shown that Q compounds bind to a molecule called S100A9 which is expressed in some white blood cells involved in the regulation of immune responses. Furthermore, it is shown that S100A9 interacts with two known pro-inflammatory receptors (Toll like receptor 4 (TLR4) and receptor of advanced glycation end products (RAGE)) and that this interaction is inhibited by Q compounds.
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