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See Latest ArticlesA bioinformatics approach for the phenotype prediction of non-synonymous single nucleotide polymorphisms in human cytochrome P450s
Drug Metabolism and Disposition, 04/15/09
Wang LL et al. - These amino acid substitutions are supposed to be the pathogenetic basis for the alteration of CYP enzyme activity and the association with disease susceptivity. This prediction analysis of nsSNPs in human CYPs would be useful for further genotype-phenotype studies on individual differences in drug metabolism and clinical response.
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