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Shire plc, the global specialty biopharmaceutical company, announces that it has decided to withdraw the European Marketing Authorization Application for DAYTRANA for the treatment of Attention Deficit Hyperactivity Disorder. A request from European regulators to conduct an additional clinical study on DAYTRANA in a European patient population combined with the recently announced planned acquisition of the worldwide rights to EQUASYM IR and XL for the treatment of ADHD are the basis for this decision.

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