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Dronedarone: An antiarrhythmic agent for the management of atrial fibrillation and atrial flutter
Formulary , 02/11/09
Coleman CI et al. - The results of an additional trial suggest that dronedarone should not be used in patients with severe heart failure, as these patients demonstrated an increased mortality risk with dronedarone treatment. Worsening renal function has also been associated with dronedarone, but the clinical relevance of this is a matter of some debate. Dronedarone is currently pending FDA approval; the agent was granted priority review in August 2008.
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