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Contrasting Measures of Adherence with Simple Drug Use, Medication Switching, and Therapeutic Duplication
Annals of Pharmacotherapy, 01/15/09

Martin BC et al. - The PDC provides a more conservative estimate of adherence than the MPR across all types of users; however, the differences between the 2 methods are more substantial for persons switching therapy and prescribed therapeutic duplication, where MPR may overstate true adherence. The PDC should be considered when a measure of adherence to a class of medications is sought, particularly in clinical situations in which multiple medications within a class are often used concurrently.

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