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Front line treatment of elderly multiple myeloma in the era of novel agents
Biologics: targets & therapy, 12/11/08
Venon MD et al. - Melphalan combined with prednisone (MP) has long been the historical treatment of reference for a large proportion of elderly myeloma (MM) patients ineligible for autologous stem cell transplantation, and is still the backbone of new regimens that include the new era of novel agents. Melphalan–prednisone–thalidomide (MPT) and melphalan-prednisone-bortezomib, proved superior to MP, currently appear to be the treatments of choice for this population.
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